It's unfortunate how the dreams of Isaiah Austin were crushed by the results of an unexpected diagnosis. He was diagnosed with Marfan Syndrome, which is a mutation in the Fibrillin (a glycoprotein) gene. Fibrillin serves as an organizing center for elastic material to be deposited on the surface of microfibrils, allowing normal stretching of tissues. This mutation leads to abnormal elastic tissues, decreasing the elasticity of tissues. Therefore, if Isaiah Austin were to overexert himself, the increased load on the heart and large blood vessels (rich in elastic tissue) could cause them to rupture, unable to expand to accommodate the increased blood flow.
It was a honorable gesture for the NBA to recognize Austin and his accomplishments.
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